Life Science Collaborative: The University of Michigan is a partner institution in the Life Science Collaborative Access Team (LS-CAT) at the Advanced Photon Source Synchrotron in Argonne, IL. LS-CAT possesses four ID beamlines equipped with Mar CCD detectors, MD2 Diffractometers, and IRELEC CATS sample changers. Our partnership in LS-CAT offers UM researchers with unfettered access to state-of-the-art facilities for macromolecular crystallography.

NMR Instrumentation: The University of Michigan possesses a 600 MHz Bruker and an 800 MHz Varian solution NMR spectrometers that are available for structural biology studies. In addition, UM researchers have access to a 900 MHz magnet at Michigan State University that can be used to perform experiments on solid-state and solution samples. Fast-spinning low-electric-field magic-angle-spinning (MAS) probe for experiments biological solids like membranes and cryoprobes for experiments on isotropic solution are available. A variety of biological systems such as proteins, DNA, RNA, bone, nanomedicines, nanoparticles, and polymorphic pharmaceutical compounds can be studied using this facility.

Center for Structural Biology: The Center for Structural Biology (CSB) provides a comprehensive structural biology capability to researchers at the University of Michigan.  At present, the Center includes three core laboratories, with plans underway to develop a cryo electron microscopy facility: 1) an X-ray diffraction facility to determine crystal structures of biological macromolecules, 2) a high-throughput protein laboratory for protein engineering and 3) a crystallization screening laboratory.